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500 Terry Francois Street 

San Francisco, CA 94158

Tel: 123-456-7890

Selected publications

  • Owen B, Davidovich C. DNA binding by polycomb-group proteins: searching for the link to CpG islands. Nucleic Acids Res. 2022 Apr 30;gkac290. doi: 10.1093/nar/gkac290. PMID: 35489059.

  • Uckelmann M, Davidovich C. An added layer of repression for human genes. Nature. 2022 Mar 30. doi: 10.1038/d41586-022-00519-3. PMID: 35354969

  • Bose T, Fridkin G, Davidovich C, Krupkin M, Dinger N, Falkovich AH, Peleg Y, Agmon I, Bashan A, Yonath A. Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds. Nucleic Acids Res. 2022 Feb 28;50(4):1815-1828. doi: 10.1093/nar/gkac052. PMID: 35137169

  • Bravo JPK, Bartnik K, Venditti L, Acker J, Gail EH, Colyer A, Davidovich C, Lamb DC, Tuma R, Calabrese AN, Borodavka A. Structural basis of rotavirus RNA chaperone displacement and RNA annealing. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2100198118. doi: 10.1073/pnas.2100198118.
    PMID: 34615715.

  • Zhang Q*, Agius SC*, Flanigan SF, Uckelmann M, Levina L, Owen BM, Davidovich C. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nature Comm. 2021. Jul 28;12(1):4592. doi: 10.1038/s41467-021-24866-3.

  • Uckelmann M, Davidovich C. Not just a writer: PRC2 as a chromatin reader. Biochem Soc Trans. 2021 Jun 30;49(3):1159-1170. doi: 10.1042/BST20200728. PMID: 34060617.

  • Davidovich C, Zhang Q. Allosteric regulation of histone lysine methyltransferases: from context-specific regulation to selective drugs. Biochem Soc Trans. 2021 Apr 30;49(2):591-607. doi: 10.1042/BST20200238. PMID: 33769454.

  • Gail EH, Shah AD, Schittenhelm RB, Davidovich C. crisscrosslinkeR: identification and visualization of protein-RNA and protein-protein interactions from crosslinking mass spectrometry. Bioinformatics (Oxford) 2020. btaa1043; doi: 10.1093/bioinformatics/btaa1043. PMID: 33346827

  • Scheer S, Bramhall M, Runting J, Russ B, Zhang Q, Flanigan SF, Zaini A, Ellemor J, Rodrigues G, Ng J, Davidovich C, Zaph C. The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation. bioRxiv 821348v2

  • Horn V*, Uckelmann M*, Zhang H, Eerland J, Aarsman I, le Paige UB, Davidovich C, Sixma TK, van Ingen H.  Structural basis of specific H2A K13/K15 ubiquitination by RNF168. Nature Comm. 2019. doi: 10.1038/s41467-019-09756-z. PMID 30988309


  • Zhang Q*, McKenzie NJ*, Warneford-Thomson R*, Gail EH, Flanigan FF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C. RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2. Nature Struct Mol Biol. 2019. doi: 10.1038/s41594-019-0197-y. PMID: 30833789


  • Wang X, Davidovich C. Targeting PRC2: RNA offers new opportunities. Oncotarget. 2017 Nov 27;8(64):107346-107347. doi: 10.18632/oncotarget.22715. PMID: 29296169


  • Wekselman I, Zimmerman E, Davidovich C, Belousoff M, Matzov D, Krupkin M, Rozenberg H, Bashan A, Friedlander G, Kjeldgaard J, Ingmer H, Lindahl L, Zengel JM, Yonath A. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure. 2017 Aug 1;25(8):1233-1241.e3. doi: 10.1016/j.str.2017.06.004. PMID: 28689968


  • Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C. Targeting of Polycomb repressive complex 2 to RNA by short repeats of consecutive guanines. Mol Cell. 2017 Mar;65(6)1056-1067; PubMed PMID: 28306504; doi: 10.1016/j.molcel.2017.02.003.


  • Auerbach-Nevo T, Baram D, Bashan A, Belousoff M, Breiner E, Davidovich C, Cimicata G, Eyal Z, Halfon Y, Krupkin M, Matzov D, Metz M, Rufayda M, Peretz M, Pick O, Pyetan E, Rozenberg H, Shalev-Benami M, Wekselman I, Zarivach R, Zimmerman E, Assis N, Bloch J, Israeli H, Kalaora R, Lim L, Sade-Falk O, Shapira T, Taha-Salaime L, Tang H, Yonath A.  Ribosomal antibiotics: contemporary challenges. Antibiotics (Basel). 2016 Jun 29;5(3). pii: E24. PubMed PMID: 27367739; doi: 10.3390/antibiotics5030024.


  • Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. 2016 May;pii: S0092-8674(16)30422-6. PubMed PMID: 27180905; doi: 10.1016/j.cell.2016.04.028.


  • Davidovich C, Cech TR. The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2. RNA. 2015 Dec;21(12):2007-22. PubMed PMID: 26574518; doi: 10.1261/rna.053918.115.



  • Davidovich C, Goodrich KJ, Gooding AR, Cech TR. A dimeric state for PRC2. Nucleic Acids Res. 2014 Aug;42(14):9236-48. doi: 10.1093/nar/gku540. Epub 2014 Jul 3. PubMed PMID: 24992961; PubMed Central PMCID: PMC4132707.

* equal contribution.

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