Contact

500 Terry Francois Street 

San Francisco, CA 94158

Tel: 123-456-7890 

Selected publications

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• Gail EH, Shah AD, Schittenhelm RB, Davidovich C. crisscrosslinkeR: identification and visualization of protein-RNA and protein-protein interactions from crosslinking mass spectrometry. Bioinformatics (Oxford) 2020. btaa1043; doi: 10.1093/bioinformatics/btaa1043. PMID: 33346827

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• Zhang Q*, Agius SC*, Flanigan SF, Levina V, Owen BM, Davidovich C. Convergent evolution between PALI1 and JARID2 for the allosteric activation of PRC2. bioRxiv 2020.05.28.122556; doi: https://doi.org/10.1101/2020.05.28.122556

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• Scheer S, Bramhall M, Runting J, Russ B, Zhang Q, Flanigan SF, Zaini A, Ellemor J, Rodrigues G, Ng J, Davidovich C, Zaph C. The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation. bioRxiv 821348v2

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• Horn V*, Uckelmann M*, Zhang H, Eerland J, Aarsman I, le Paige UB, Davidovich C, Sixma TK, van Ingen H.  Structural basis of specific H2A K13/K15 ubiquitination by RNF168. Nature Comm. 2019. doi: 10.1038/s41467-019-09756-z. PMID 30988309

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• Zhang Q*, McKenzie NJ*, Warneford-Thomson R*, Gail EH, Flanigan FF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C. RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2. Nature Struct Mol Biol. 2019. doi: 10.1038/s41594-019-0197-y. PMID: 30833789

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• Wang X, Davidovich C. Targeting PRC2: RNA offers new opportunities. Oncotarget. 2017 Nov 27;8(64):107346-107347. doi: 10.18632/oncotarget.22715. PMID: 29296169

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• Wekselman I, Zimmerman E, Davidovich C, Belousoff M, Matzov D, Krupkin M, Rozenberg H, Bashan A, Friedlander G, Kjeldgaard J, Ingmer H, Lindahl L, Zengel JM, Yonath A. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure. 2017 Aug 1;25(8):1233-1241.e3. doi: 10.1016/j.str.2017.06.004. PMID: 28689968

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• Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C. Targeting of Polycomb repressive complex 2 to RNA by short repeats of consecutive guanines. Mol Cell. 2017 Mar;65(6)1056-1067; PubMed PMID: 28306504; doi: 10.1016/j.molcel.2017.02.003.

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• Auerbach-Nevo T, Baram D, Bashan A, Belousoff M, Breiner E, Davidovich C, Cimicata G, Eyal Z, Halfon Y, Krupkin M, Matzov D, Metz M, Rufayda M, Peretz M, Pick O, Pyetan E, Rozenberg H, Shalev-Benami M, Wekselman I, Zarivach R, Zimmerman E, Assis N, Bloch J, Israeli H, Kalaora R, Lim L, Sade-Falk O, Shapira T, Taha-Salaime L, Tang H, Yonath A.  Ribosomal antibiotics: contemporary challenges. Antibiotics (Basel). 2016 Jun 29;5(3). pii: E24. PubMed PMID: 27367739; doi: 10.3390/antibiotics5030024.

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• Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. 2016 May;pii: S0092-8674(16)30422-6. PubMed PMID: 27180905; doi: 10.1016/j.cell.2016.04.028.

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• Davidovich C, Cech TR. The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2. RNA. 2015 Dec;21(12):2007-22. PubMed PMID: 26574518; doi: 10.1261/rna.053918.115.

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• Davidovich C, Wang X, Cifuentes-Rojas C, Goodrich KJ, Gooding AR, Lee JT, Cech TR. Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA. Mol Cell. 2015 Feb 5;57(3):552-8. doi: 10.1016/j.molcel.2014.12.017. Epub 2015 Jan 15. PubMed PMID: 25601759; PubMed Central PMCID: PMC4320675.

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• Davidovich C, Goodrich KJ, Gooding AR, Cech TR. A dimeric state for PRC2. Nucleic Acids Res. 2014 Aug;42(14):9236-48. doi: 10.1093/nar/gku540. Epub 2014 Jul 3. PubMed PMID: 24992961; PubMed Central PMCID: PMC4132707.

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• Davidovich C, Zheng L, Goodrich KJ, Cech TR. Promiscuous RNA binding by Polycomb repressive complex 2. Nature Struct Mol Biol. 2013 Nov;20(11):1250-7. doi: 10.1038/nsmb.2679. Epub 2013 Sep 29. PubMed PMID: 24077223; PubMed Central PMCID: PMC3823624.

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• Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1983-8. doi: 10.1073/pnas.0914100107. Epub 2010 Jan 11. PubMed PMID: 20080686; PubMed Central PMCID: PMC2804743.

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• Davidovich C, Belousoff M, Bashan A, Yonath A. The evolving ribosome: from non-coded peptide bond formation to sophisticated translation machinery. Res Microbiol. 2009 Sep;160(7):487-92. doi: 10.1016/j.resmic.2009.07.004. Epub 2009 Jul 18. Review. PubMed PMID: 19619641.

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• Davidovich C, Bashan A, Yonath A. Structural basis for cross-resistance to ribosomal PTC antibiotics. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20665-70. doi: 10.1073/pnas.0810826105. Epub 2008 Dec 19. PubMed PMID: 19098107; PubMed Central PMCID: PMC2605634.

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• Davidovich C, Bashan A, Auerbach-Nevo T, Yaggie RD, Gontarek RR, Yonath A. Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4291-6. Epub 2007 Mar 8. PubMed PMID: 17360517; PubMed Central PMCID: PMC1817833.

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* equal contribution.